AECOS® (American-European Congress of Ophthalmic Surgery) was pleased to sponsor a leading accelerated cross-linking study, ACOS-KXL-001, in which 83 clinical sites offered accelerated cross-linking throughout the US. AECOS received approval from the FDA to initiate the phase 3, multicenter, randomized, controlled evaluation of the safety and efficacy of corneal collagen cross-linking in eyes with keratoconus or corneal ectasia after refractive surgery. The study exclusively utilized Avedro’s riboflavin and KXL system for accelerated cross-linking. Patients with keratoconus and corneal ectasia were recruited nationwide to evaluate and compare the safety and efficacy of three treatment regimens for corneal collagen cross-linking performed with Avedro’s riboflavin and KXL System for reducing corneal curvature. Corneal collagen cross-linking has been commonly used as the first-line method to restore corneal stability in keratoconic and corneal ectatic eyes in Europe and throughout the world for many years. The AECOS study was concluded in June 2016 with very favorable results. It is the largest body of corneal cross-linking data in the world.
Principal Investigators: AECOS Corneal Cross-Linking Clinical Sites:
| Last Name | First Name | Practice Name | Address | Phone Number | Website |
|---|---|---|---|---|---|
| Aran | Alberto | The Laser Center of Coral Gables | Coral Gables, FL | 305-461-0003 | tlccoralgables.com |
| Ashford | William | Eye Surgery and Laser Center | Jackson, MS | 601-985-9120 | eyegroupms.com |
| Ayres | Brandon | Ophthalmic Partners of PA, P.C. | Bala Cynwyd, PA | 484-434-2700 | oppdoctors.com |
| Bagan | Steven | Bagan Strinden Vision | Fargo, ND | 701-293-8242 | laserprofessionals.com |
| Batra | Nicholas | Batra Vision Medical Group | San Leandro, CA | 510-276-1212 | batravision.com |
| Beckman | Kenneth | Comprehensive Eye Care of Central Ohio | Westerville, OH | 614-890-5692 | compeyecare.com |
| Boland | Thomas | Northeastern Eye Institute | Scranton, PA | 800-334-2233 | neivision.com |
| Braverman | Stanley | Braverman Eye Center | Hallandale, FL | 954-458-2212 | bravermaneyecenter.com |
| Bucci | Frank A. | Bucci Laser Vision Institute | Wilkes-Barre, PA | 570-825-5949 | buccivision.com |
| Chamberlain | Winston | Casey Eye Institute/OHSU | Portland, OR | 503-494-3000 | ohsu.edu/ |
| Chu | Y. Ralph | Chu Vision Institute | Bloomington, MN | 952-835-1235 | chuvision.com |
| Chung | Gary | Evergreen Eye Center | Federal Way, WA | 800-254-4934 | evergreeneye.com |
| Clinch | Thomas | Eye Doctors of Washington | Chevy Chase, MD | 301-215-7100 | edow.com |
| Dell | Steven J. | Dell Laser Consultants | Austin, TX | 512-347-0255 | dellvision.com |
| Desai | Neel | The Eye Institute of West Florida | Largo, FL | 727-581-8706 | eyespecialist.com |
| Doe | Erin | Berkeley Eye Center | Houston, TX | 713-526-3937 | berkeleyeye.com |
| Dunn | Steven | Michigan Cornea Consultants, PC | Southfield, MI | 248-350-1130 | michigancornea.com |
| Ellis | Dean | Kansas LasikPlus, P.A. | Leawood, KS | 866-921-2392 | lasikplus.com/ |
| Fintelmann | Robert | Barnet Dulaney Perkins Eye Center | Phoenix, AZ | 866-742-6581 | goodeyes.com |
| Fram | Nicole | Advanced Vision Care | Los Angeles, CA | 310-229-1220 | advancedvisioncare.com |
| Gangadhar | Dasa | Grene Vision Group | Wichita, KS | 316-684-5158 | grenevisiongroup.com |
| Gira | Joseph P. | Ophthalmology Consultants | Des Peres, MO | 314-909-0633 | ocstl.com |
| Gordon | Richard | Ramapo Ophthalmology Associates, LLP | Pomona, NY | 845-362-1450 | ramapoeye.com |
| Grace | Colleen | Henry Ford Health System | Detroit, MI | 800-436-7936 | henryford.com/ |
| Greenberg | Jason | LasikPlus Vision Center | Louisville, KY | 866-921-2392 | lasikplus.com/ |
| Greiner | Mark | University of Iowa Hospitals and Clinics | Coralville, IA | 319-467-2000 | uihealthcare.org/irl |
| Groden | Lewis | LCA-Vision Inc. | Tampa, FL | 813-639-3937 | lasikplus.com |
| Herschel | Mark | Herschel Lasik | Orlando, FL | 407-894-8081 | lasikeyeorlando.com |
| Himmel | Kenneth | Eye Associates of New Mexico | Albuquerque, NM | 505-883-6800 | eyenm.com |
| Ing | Jeffrey | Delta Eye Medical Group | Stockton, CA | 209-478-1797 | deltaeyemedicalgroup.com |
| Iuorno | Joseph D. | Commonwealth Eye Associates | Richmond, VA | 804-740-7474 | commonwealtheye.com |
| Jain | Vivek | Beach Eye Care | Virginia Beach, VA | 757-425-5550 | beacheyecare.com |
| Jones | Michael Paul | Illinois Eye Surgeons | Belleville, IL | 618-234-1774 | illinoiseye.com |
| Khachikian | Stephen | Black Hills Regional Eye Institute | Rapid City, SD | 605-341-2000 | lasikrapidcity.com |
| Kuck | Paul | Gundersen Clinic, Ltd. | La Crosse, WI | 608-775-2191 | gundersenhealth.org/vision |
| Kugler | Lance | Kugler Vision, PC | Omaha, NE | 402-558-2211 | lasikomaha.com |
| Labor | Phillips | Eye Consultants of Texas | Grapevine, TX | 817-410-2030 | eyectexas.com |
| Lehmann | James | Focal Point Vision | San Antonio, TX | 210-614-3600 | focalpointvision.com |
| Liang | Keith | Center for Sight | Sacramento, CA | 916-446-2020 | liangvision.com |
| Loden | James | Loden Vision Centers | Goodlettsville, TN | 615-859-3937 | lodenvision.com |
| Manche | Edward | Stanford University School of Medicine | Palo Alto, CA | 650-498-7020 | eyelaser.stanford.edu |
| Melki | Samir | Boston Eye Group | Brookline, MA | 617-566-0062 | bostonlaser.com |
| Meskin | Seth | Eye Physicians and Surgeons, PC | Milford, CT | 203-878-1236 | eyevision2020.net |
| Mian | Shahzad | University of Michigan | Ann Arbor, MI | 734-763-8122 | kellogg.umich.edu |
| Miedziak | Anita | Princeton Eye Group | Princeton, NJ | 609-921-9437 | princetoneyegroup.com |
| Mishra | Gautam | Schein Ernst Eye Associates | Harrisburg, PA | 717-233-3937 | seegreat.net |
| Moshirfar | Majid | The Moran Eye Center, University of Utah | Salt Lake City, UT | 801-581-2352 | healthcare.utah.edu/moran |
| Newman | Leonard | Newman Lasik Centers | Sacramento, CA | 916-256-1900 | newmanlasik.com |
| Orlin | Stephen E. | Scheie Eye Institute, Penn School of Medicine | Philadelphia, PA | 215-662-9062 | uphs.upenn.edu/ophthalmology |
| Paglen | Patrick | Kaiser Permanente | Santa Rosa, CA | 707-566-5232 | kplaservisioncorrection.com |
| Parker | John | John Parker, MD (private office) | Birmingham, AL | 205-933-1077 | johnsparkermd.com |
| Pepose | Jay | Pepose Vision Institute / Lifelong Vision Foundation | Chesterfield, MO | 636-728-0111 | peposevision.com |
| Petashnick | Daniel | Manchester Ophthalmology | Manchester, CT | 860-649-5177 | lasikmanchester.com |
| Pramanik | Sudeep | Mid-Atlantic Cornea Consultants | Towson, MD | 443-849-2106 | midatlanticcornea.com/ |
| Raizman | Michael | Ophthalmic Consultants of Boston | Waltham, MA | 781-487-2200 | eyeboston.com |
| Ramirez | Ruben | Buena Vista Eyecare | El Paso, TX | 915-630-6463 | buenavistaelpaso.com |
| Rapuano | Christopher | Corneal Associates, PC at Wills Eye Institute | Philadelphia, PA | 215-928-3180 | cornealdocs.com |
| Richheimer | William | Mile High Corneal Specialists, PC | Denver, CO | 303-482-1300 | milehighcornea.com |
| Rivera | Lilia | Lilia Rivera, MD | San Juan, P.R. | 787-250-7746 | |
| Rivera | Robert P. | Hoopes Vision | Draper, UT | 855-570-2949 | hoopesvision.com |
| Rosenfeld | Steven | Delray Eye Associates, PA | Delray Beach, FL | 561-498-8100 | delrayeye.com |
| Shah | Pulin | Ochsner Medical Center | New Orleans, LA | 504-899-9311 | ochsner.org |
| Shah | Ravindra A. | Eyecare Medical Group | Portland, ME | 888-374-2020 | eyecaremed.com |
| Sheppard | John | Virginia Eye Consultants | Norfolk, VA | 757-622-2200 | virginiaeyeconsultants.com |
| Shih | Carolyn | North Shore LIJ Health Systems | Great Neck, NY | 516-708-2540 | northshorelij.com |
| Sierra | Patricia | Grutzmacher, Lewis and Sierra | Sacramento, CA | 916-649-1515 | eyelasik.com |
| Silk | Wesam | Silk Vision & Surgical Center | Annandale, VA | 703-876-9700 | silkvision.net |
| Slade | Stephen | Slade and Baker Vision Center | Houston, TX | 713-626-5544 | visiontexas.com |
| Smith | Byron | The Eye Clinic Surgicenter | Billings, MT | 406-252-6608 | theeyeclinicsurgicenter.com |
| Solomon | Jonathan | Solomon Eye Physicians & Surgeons | Bowie, MD | 301-464-1885 | solomoneyeassociates.com |
| Stevens | Garth | Eye Care Center of Virginia | Richmond, VA | 804-343-2020 | lasikcenterva.com |
| Stone | Donald | Dean McGee Eye Institute | Oklahoma City, OK | 405-271-6060 | mei.org |
| Straiko | Michael | Devers Eye Institute | Portland, OR | 503-413-8202 | legacyhealth.org |
| Sutton | Gregory | Eye Surgical Associates | Lincoln, NE | 800-742-39516e4 | esa-neb.com |
| Thompson | Vance | Vance Thompson Vision | Sioux Falls, SD | 605-361-3937 | vancethompsonvision.com |
| Verdier | David | Verdier Eye Center, P.L.C | Grand Rapids, MI | 616-949-2001 | verdiereyecenter.com |
| Vukich | John | Davis Duehr Dean Eye Care | Madison, WI | 608-282-2000 | deancare.com |
| Wang | Ming Xu | Wang Vision Institute | Nashville, TN | 615-321-8881 | wangvisioninstitute.com |
| Weisenthal | Robert | CNY Eye Care | Syracuse, NY | 315 445 1577 | cnyeyecare.com |
| Wellish | Kent | Wellish Vision Institute | Las Vegas, NV | 702-733-2020 | wellishvision.com |
| Wolsey | Darcy | The Eye Institute of Utah | Salt Lake City, UT | 800-760-4171 | theeyeinstitute.com |
| Woodcock | Michael | Carolina Vision Center | Fayetteville, NC | 910-485-3937 | carolinavisioncenter.com |
| Wright | Paul | Wright Vision Center | Rapid City, SD | 877-576-0202 | wrightvisioncenter.com |