AECOS Corneal Cross-Linking Clinical Trial

AECOS® (American-European Congress of Ophthalmic Surgery) was pleased to sponsor a leading accelerated cross-linking study, ACOS-KXL-001, in which 83 clinical sites offered accelerated cross-linking throughout the US. AECOS received approval from the FDA to initiate the phase 3, multicenter, randomized, controlled evaluation of the safety and efficacy of corneal collagen cross-linking in eyes with keratoconus or corneal ectasia after refractive surgery. The study exclusively utilized Avedro’s riboflavin and KXL system for accelerated cross-linking.  Patients with keratoconus and corneal ectasia were recruited nationwide to evaluate and compare the safety and efficacy of three treatment regimens for corneal collagen cross-linking performed with Avedro’s riboflavin and KXL System for reducing corneal curvature. Corneal collagen cross-linking has been commonly used as the first-line method to restore corneal stability in keratoconic and corneal ectatic eyes in Europe and throughout the world for many years.  The AECOS study was concluded in June 2016 with very favorable results.  It is the largest body of corneal cross-linking data in the world.

Principal Investigators: AECOS Corneal Cross-Linking Clinical Sites:

Last Name First Name Practice Name Address Phone Number Website
Aran Alberto The Laser Center of Coral Gables Coral Gables, FL 305-461-0003 tlccoralgables.com
Ashford William Eye Surgery and Laser Center Jackson, MS 601-985-9120 eyegroupms.com
Ayres Brandon Ophthalmic Partners of PA, P.C. Bala Cynwyd, PA 484-434-2700 oppdoctors.com
Bagan Steven Bagan Strinden Vision Fargo, ND 701-293-8242 laserprofessionals.com
Batra Nicholas Batra Vision Medical Group San Leandro, CA 510-276-1212 batravision.com
Beckman Kenneth Comprehensive Eye Care of Central Ohio Westerville, OH 614-890-5692 compeyecare.com
Boland Thomas Northeastern Eye Institute Scranton, PA 800-334-2233 neivision.com
Braverman Stanley Braverman Eye Center Hallandale, FL 954-458-2212 bravermaneyecenter.com
Bucci Frank A. Bucci Laser Vision Institute Wilkes-Barre, PA 570-825-5949 buccivision.com
Chamberlain Winston Casey Eye Institute/OHSU Portland, OR 503-494-3000 ohsu.edu/
Chu Y. Ralph Chu Vision Institute Bloomington, MN 952-835-1235 chuvision.com
Chung Gary Evergreen Eye Center Federal Way, WA 800-254-4934 evergreeneye.com
Clinch Thomas Eye Doctors of Washington Chevy Chase, MD 301-215-7100 edow.com
Dell Steven J. Dell Laser Consultants Austin, TX 512-347-0255 dellvision.com
Desai Neel The Eye Institute of West Florida Largo, FL 727-581-8706 eyespecialist.com
Doe Erin Berkeley Eye Center Houston, TX 713-526-3937 berkeleyeye.com
Dunn Steven Michigan Cornea Consultants, PC Southfield, MI 248-350-1130 michigancornea.com
Ellis Dean Kansas LasikPlus, P.A. Leawood, KS 866-921-2392 lasikplus.com/
Fintelmann Robert Barnet Dulaney Perkins Eye Center Phoenix, AZ 866-742-6581 goodeyes.com
Fram Nicole Advanced Vision Care Los Angeles, CA 310-229-1220 advancedvisioncare.com
Gangadhar Dasa Grene Vision Group Wichita, KS 316-684-5158 grenevisiongroup.com
Gira Joseph P. Ophthalmology Consultants Des Peres, MO 314-909-0633 ocstl.com
Gordon Richard Ramapo Ophthalmology Associates, LLP Pomona, NY 845-362-1450 ramapoeye.com
Grace Colleen Henry Ford Health System Detroit, MI 800-436-7936 henryford.com/
Greenberg Jason LasikPlus Vision Center Louisville, KY 866-921-2392 lasikplus.com/
Greiner Mark University of Iowa Hospitals and Clinics Coralville, IA 319-467-2000 uihealthcare.org/irl
Groden Lewis LCA-Vision Inc. Tampa, FL 813-639-3937 lasikplus.com
Herschel Mark Herschel Lasik Orlando, FL 407-894-8081 lasikeyeorlando.com
Himmel Kenneth Eye Associates of New Mexico Albuquerque, NM 505-883-6800 eyenm.com
Ing Jeffrey Delta Eye Medical Group Stockton, CA 209-478-1797 deltaeyemedicalgroup.com
Iuorno Joseph D. Commonwealth Eye Associates Richmond, VA 804-740-7474 commonwealtheye.com
Jain Vivek Beach Eye Care Virginia Beach, VA 757-425-5550 beacheyecare.com
Jones Michael Paul Illinois Eye Surgeons Belleville, IL 618-234-1774 illinoiseye.com
Khachikian Stephen Black Hills Regional Eye Institute Rapid City, SD 605-341-2000 lasikrapidcity.com
Kuck Paul Gundersen Clinic, Ltd. La Crosse, WI 608-775-2191 gundersenhealth.org/vision
Kugler Lance Kugler Vision, PC Omaha, NE 402-558-2211 lasikomaha.com
Labor Phillips Eye Consultants of Texas Grapevine, TX 817-410-2030 eyectexas.com
Lehmann James Focal Point Vision San Antonio, TX 210-614-3600 focalpointvision.com
Liang Keith Center for Sight Sacramento, CA 916-446-2020 liangvision.com
Loden James Loden Vision Centers Goodlettsville, TN 615-859-3937 lodenvision.com
Manche Edward Stanford University School of Medicine Palo Alto, CA 650-498-7020 eyelaser.stanford.edu
Melki Samir Boston Eye Group Brookline, MA 617-566-0062 bostonlaser.com
Meskin Seth Eye Physicians and Surgeons, PC Milford, CT 203-878-1236 eyevision2020.net
Mian Shahzad University of Michigan Ann Arbor, MI 734-763-8122 kellogg.umich.edu
Miedziak Anita Princeton Eye Group Princeton, NJ 609-921-9437 princetoneyegroup.com
Mishra Gautam Schein Ernst Eye Associates Harrisburg, PA 717-233-3937 seegreat.net
Moshirfar Majid The Moran Eye Center, University of Utah Salt Lake City, UT 801-581-2352 healthcare.utah.edu/moran
Newman Leonard Newman Lasik Centers Sacramento, CA 916-256-1900 newmanlasik.com
Orlin Stephen E. Scheie Eye Institute, Penn School of Medicine Philadelphia, PA 215-662-9062 uphs.upenn.edu/ophthalmology
Paglen Patrick Kaiser Permanente Santa Rosa, CA 707-566-5232 kplaservisioncorrection.com
Parker John John Parker, MD (private office) Birmingham, AL 205-933-1077 johnsparkermd.com
Pepose Jay Pepose Vision Institute / Lifelong Vision Foundation Chesterfield, MO 636-728-0111 peposevision.com
Petashnick Daniel Manchester Ophthalmology Manchester, CT 860-649-5177 lasikmanchester.com
Pramanik Sudeep Mid-Atlantic Cornea Consultants Towson, MD 443-849-2106 midatlanticcornea.com/
Raizman Michael Ophthalmic Consultants of Boston Waltham, MA 781-487-2200 eyeboston.com
Ramirez Ruben Buena Vista Eyecare El Paso, TX 915-630-6463 buenavistaelpaso.com
Rapuano Christopher Corneal Associates, PC at Wills Eye Institute Philadelphia, PA 215-928-3180 cornealdocs.com
Richheimer William Mile High Corneal Specialists, PC Denver, CO 303-482-1300 milehighcornea.com
Rivera Lilia Lilia Rivera, MD San Juan, P.R. 787-250-7746
Rivera Robert P. Hoopes Vision Draper, UT 855-570-2949 hoopesvision.com
Rosenfeld Steven Delray Eye Associates, PA Delray Beach, FL 561-498-8100 delrayeye.com
Shah Pulin Ochsner Medical Center New Orleans, LA 504-899-9311 ochsner.org
Shah Ravindra A. Eyecare Medical Group Portland, ME 888-374-2020 eyecaremed.com
Sheppard John Virginia Eye Consultants Norfolk, VA 757-622-2200 virginiaeyeconsultants.com
Shih Carolyn North Shore LIJ Health Systems Great Neck, NY 516-708-2540 northshorelij.com
Sierra Patricia Grutzmacher, Lewis and Sierra Sacramento, CA 916-649-1515 eyelasik.com
Silk Wesam Silk Vision & Surgical Center Annandale, VA 703-876-9700 silkvision.net
Slade Stephen Slade and Baker Vision Center Houston, TX 713-626-5544 visiontexas.com
Smith Byron The Eye Clinic Surgicenter Billings, MT 406-252-6608 theeyeclinicsurgicenter.com
Solomon Jonathan Solomon Eye Physicians & Surgeons Bowie, MD 301-464-1885 solomoneyeassociates.com
Stevens Garth Eye Care Center of Virginia Richmond, VA 804-343-2020 lasikcenterva.com
Stone Donald Dean McGee Eye Institute Oklahoma City, OK 405-271-6060 mei.org
Straiko Michael Devers Eye Institute Portland, OR 503-413-8202 legacyhealth.org
Sutton Gregory Eye Surgical Associates Lincoln, NE 800-742-39516e4 esa-neb.com
Thompson Vance Vance Thompson Vision Sioux Falls, SD 605-361-3937 vancethompsonvision.com
Verdier David Verdier Eye Center, P.L.C Grand Rapids, MI 616-949-2001 verdiereyecenter.com
Vukich John Davis Duehr Dean Eye Care Madison, WI 608-282-2000 deancare.com
Wang Ming Xu Wang Vision Institute Nashville, TN 615-321-8881 wangvisioninstitute.com
Weisenthal Robert CNY Eye Care Syracuse, NY 315 445 1577 cnyeyecare.com
Wellish Kent Wellish Vision Institute Las Vegas, NV 702-733-2020 wellishvision.com
Wolsey Darcy The Eye Institute of Utah Salt Lake City, UT 800-760-4171 theeyeinstitute.com
Woodcock Michael Carolina Vision Center Fayetteville, NC 910-485-3937 carolinavisioncenter.com
Wright Paul Wright Vision Center Rapid City, SD 877-576-0202 wrightvisioncenter.com